The recommended first-line management of advanced ovarian cancer comprises surgical staging and cytoreductive surgery followed by platinum-based chemotherapy. The response rate for first-line platinum-based chemotherapy is ~80%, although ...

METTL3 (methyltransferase-like 3) mediates the N6-methyladenosine (m6A) methylation of mRNA, which affects the stability of mRNA and its translation into protein. METTL3 also binds chromatin, but the role of METTL3 and m6A methylation in ch...